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The pKa of hydrochloride salt of amphetamine is equal to 9.9.

(1) The major species present in blood, buffered at pH = 7.4, is amphetamine.

(2) The major species present in blood, buffered at pH = 7.4, is amphetamine hydrochloride.

(3) Amphetamine hydrochloride is behaving as an acid in the above equation.

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