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In a globular protein in water solution, which amino acid side chain would most likely be in the interior of the protein?

(A) The isobutyl side chain of leucine.

(B) The hydroxymethyl side chain of serine.

(C) The acetate side chain of aspartate.

(D) The acetamide side chain of asparagine.

(E) The 4-aminopropyl side chain of lysine.